Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10712738 | 0.91 | POLB (0.46) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL9788299 | 0.79 | MAPK14 (0.46) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL10357494 | 0.79 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1NPSR1MAPK1 | |
| SCHEMBL10357498 | 0.77 | POLB (0.50) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL10357432 | 0.76 | CCNE2 (0.42) | KMT2AMEN1ALDH1A1NPSR1POLB | |
| SCHEMBL10357404 | 0.74 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL10713454 | 0.73 | LMNA (0.41) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL10357760 | 0.72 | POLB (0.49) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL10357410 | 0.71 | POLB (0.41) | ALDH1A1POLBMAPK1 | |
| Potassium Ion SCHEMBL10922245 | 0.70 | CYP2C9 (0.39) | KMT2AMEN1ALDH1A1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707181-A | 1-aryl-1,4-dihydro-4-oxo-3,5-dicarboxypyridazine derivatives and their use as plant growth regulators and hybridizing agents | ROHM AND HAAS COMPANY (US) | 1987-11-17 | — | — | US | disclosed |