Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788337 | 0.91 | NR4A3 (0.50) | MAPK14SMN1; SMN2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL10714947 | 0.79 | KMT2A (0.41) | MAPK14SMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL10813419 | 0.79 | RAB9A (0.46) | MAPK14SMN1; SMN2RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL9788273 | 0.76 | NR4A3 (0.67) | MAPK14SMN1; SMN2RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL9788259 | 0.76 | CCNE2 (0.41) | MAPK14SMN1; SMN2L3MBTL1LMNAMEN1 | |
| SCHEMBL9788253 | 0.74 | NR4A3 (0.56) | MAPK14RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL9788312 | 0.72 | RAB9A (0.40) | RAB9AALDH1A1L3MBTL1NPC1LMNA | |
| SCHEMBL9788244 | 0.72 | NR4A3 (0.53) | MAPK14SMN1; SMN2RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL9005834 | 0.71 | NR4A3 (0.52) | SMN1; SMN2RAB9AALDH1A1L3MBTL1NPC1 | |
| SCHEMBL122191 | 0.70 | NR4A3 (0.51) | SMN1; SMN2RAB9AALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5062880-A | Male plant sterility | MONSANTO COMPANY (US) | 1991-11-05 | — | — | US | disclosed |
| US-4732603-A | ANTIFERTILITY AGENTS | ROHM AND HAAS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |