Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | CTSH | P09668 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277428 | 0.78 | CTSK (0.37) | CTSKCTSLCTSBCTSHREN | |
| Bromide SCHEMBL10716005 | 0.77 | CTSK (0.36) | CTSKCTSLCTSBCTSHREN | |
| Hydrochloric Acid SCHEMBL7284520 | 0.77 | CTSK (0.36) | CTSKCTSLCTSBCTSHREN | |
| SCHEMBL14111950 | 0.70 | CTSK (0.41) | CTSKCTSLCTSBCTSHMETAP2 | |
| SCHEMBL13610018 | 0.70 | CTSK (0.44) | CTSKCTSLCTSBCTSHLTA4H | |
| SCHEMBL27505423 | 0.70 | REN (0.39) | CTSKCTSLCTSBCTSHMETAP2 | |
| SCHEMBL15279268 | 0.69 | CTSK (0.40) | CTSKCTSLCTSBCTSH | |
| SCHEMBL3806162 | 0.68 | METAP2 (0.44) | CTSKCTSLCTSBCTSHMETAP2 | |
| SCHEMBL240252 | 0.68 | METAP2 (0.44) | CTSKCTSLCTSBCTSHMETAP2 | |
| SCHEMBL702586 | 0.68 | METAP2 (0.44) | CTSKCTSLCTSBCTSHMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | claimed |
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |