Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717419 | 0.81 | CTSK (0.52) | CTSKELANECTSSCTSLCTSB | |
| SCHEMBL9645985 | 0.77 | ACE2 (0.68) | CTSKELANEACE2CTSSCTSL | |
| SCHEMBL15397862 | 0.76 | ACE2 (0.71) | CTSKELANEACE2CTSSCTSL | |
| SCHEMBL7422252 | 0.76 | CTSK (0.67) | CTSKACE2CTSSCTSLCTSB | |
| SCHEMBL6841176 | 0.76 | CTSK (0.67) | CTSKACE2CTSSCTSLCTSB | |
| SCHEMBL27926954 | 0.76 | CTSK (0.67) | CTSKACE2CTSSCTSLCTSB | |
| SCHEMBL10718387 | 0.75 | CTSK (0.54) | CTSKACE2CTSSCTSLCTSB | |
| SCHEMBL12942520 | 0.75 | ELANE (0.61) | CTSKELANEACE2CTSSCTSL | |
| SCHEMBL2723504 | 0.75 | CTSK (0.62) | CTSKCTSSCTSLCTSB | |
| SCHEMBL14609392 | 0.75 | CTSK (0.74) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |
| EP-0209848-A2 | Enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | disclosed |