Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.67 |
| ▸ | CTSS | P25774 | 4/20 | 0.62 |
| ▸ | CTSL | P07711 | 4/20 | 0.62 |
| ▸ | CTSB | P07858 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926954 | 1.00 | CTSK (0.67) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL7422252 | 1.00 | CTSK (0.67) | CTSKCTSSCTSLCTSBATM | |
| Cyclohexane SCHEMBL8924640 | 0.93 | CTSK (0.60) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL13534727 | 0.89 | NPC1 (0.65) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL4033719 | 0.89 | NPC1 (0.65) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL14514052 | 0.88 | CTSK (0.75) | CTSKCTSSCTSLCTSB | |
| SCHEMBL18848786 | 0.88 | CTSK (0.75) | CTSKCTSSCTSLCTSB | |
| SCHEMBL10108119 | 0.87 | CTSK (0.55) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL5268187 | 0.86 | ATM (0.59) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL1547277 | 0.86 | ATM (0.59) | CTSKCTSSCTSLCTSBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130023463-A1 | HIV PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | US | disclosed |
| US-8193227-B2 | HIV protease inhibiting compounds | ABBOTT LABORATORIES (US) | 2012-06-05 | — | — | US | disclosed |
| US-20110003827-A1 | HIV protease inhibiting compounds | ABBVIE INC. | 2011-01-06 | — | — | US | disclosed |
| US-7528140-B2 | Substituted pyrrolo[3,2-d]pyrimidines as glycogen synthase kinase (GSK) inhibitors | TEIJIN LIMITED (JP) | 2009-05-05 | — | — | US | disclosed |
| US-7528140-B2 | Substituted pyrrolo[3,2-d]pyrimidines as glycogen synthase kinase (GSK) inhibitors | TEIJIN LIMITED (JP) | 2009-05-05 | — | — | US | disclosed |
| CN-1420882-A | Substd. oxoazaheterocyclyl compounds | AVENTIS PHARM PROD INC (US) | 2003-05-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003827-A1 | HIV protease inhibiting compounds | SERPINB1, HPN, DNPEP | CTSK 76/4885CTSS 62/4885CTSL 18/4885 |
| US-20130023463-A1 | HIV PROTEASE INHIBITING COMPOUNDS | SERPINB1, HPN, DNPEP | CTSK 76/4885CTSS 62/4885CTSL 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.