Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MPO | P05164 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 3/20 | 0.55 |
| ▸ | HTR1D | P28221 | 3/20 | 0.55 |
| ▸ | HTR1B | P28222 | 3/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HTR5A | P47898 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.53 |
| ▸ | ICMT | O60725 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719022 | 0.88 | MPO (0.60) | KDM4EALDH1A1NPSR1CYP2D6KMT2A | |
| SCHEMBL10716570 | 0.84 | HTR1A (0.66) | NPSR1LMNATDP1CYP2D6MEN1 | |
| SCHEMBL8787799 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1NPSR1LMNATDP1 | |
| SCHEMBL10717720 | 0.83 | ICMT (0.53) | CYP2D6MEN1HTR2CKMT2AMPO | |
| Methane SCHEMBL10718960 | 0.83 | HTR1A (0.64) | NPSR1LMNATDP1CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL10716674 | 0.83 | HTR1A (0.64) | NPSR1LMNATDP1CYP2D6MEN1 | |
| SCHEMBL12352649 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1NPSR1LMNATDP1 | |
| SCHEMBL10716765 | 0.82 | HTR2A (0.60) | KMT2AMPOHTR2ASNCA | |
| SCHEMBL10717762 | 0.82 | HTR1D (0.67) | LMNACYP2D6HTR2CKMT2AMPO | |
| SCHEMBL11359819 | 0.82 | HTR1A (0.71) | KDM4EALDH1A1NPSR1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4650810-A | OR INDOLE-5-THIOACETAMIDES | GLAXO GROUP LIMITED (GB) | 1987-03-17 | — | — | US | disclosed |