Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717754 | 0.90 | ALDH1A1 (0.52) | ALDH1A1LMNAPKMMAPTATM | |
| SCHEMBL10731823 | 0.86 | MAPT (0.59) | ALDH1A1LMNAPKMMAPTATM | |
| SCHEMBL10730945 | 0.83 | PKM (0.58) | ALDH1A1LMNAPKMMAPTATM | |
| SCHEMBL10732434 | 0.83 | NPC1 (0.47) | ALDH1A1LMNAPKMMAPTATM | |
| SCHEMBL10732444 | 0.83 | MAPT (0.49) | ALDH1A1LMNAPKMMAPTATM | |
| SCHEMBL10732657 | 0.83 | PKM (0.47) | ALDH1A1LMNAPKMMAPTATM | |
| SCHEMBL10732117 | 0.81 | PKM (0.52) | ALDH1A1LMNAPKMMAPTATM | |
| SCHEMBL10726208 | 0.81 | PKM (0.52) | ALDH1A1LMNAPKMMAPTATM | |
| SCHEMBL10730546 | 0.80 | PKM (0.44) | ALDH1A1LMNAPKMMAPTATM | |
| SCHEMBL10726223 | 0.80 | NPC1 (0.49) | ALDH1A1LMNAPKMMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |