Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732434 | 0.90 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL10717754 | 0.87 | ALDH1A1 (0.52) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL10732444 | 0.86 | MAPT (0.49) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL10725744 | 0.86 | RAB9A (0.51) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL10726208 | 0.84 | PKM (0.52) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL10730546 | 0.83 | PKM (0.44) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL10731823 | 0.82 | MAPT (0.59) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL10729295 | 0.81 | ALDH1A1 (0.45) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL10731309 | 0.80 | KMT2A (0.46) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL10716660 | 0.80 | ALDH1A1 (0.49) | NPC1RAB9AMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |