Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 5/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802253 | 0.89 | ADRB2 (0.57) | ADRB2KCNH2KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL7599453 | 0.85 | ADRB2 (0.65) | ADRB2LMNAKCNH2KDM4ETOP2A | |
| SCHEMBL4476600 | 0.84 | ADRB2 (0.55) | ADRB2LMNAKCNH2TOP2ATOP2B | |
| SCHEMBL9188190 | 0.84 | ADRB2 (0.61) | ADRB2LMNAKCNH2KDM4ETOP2A | |
| SCHEMBL7011806 | 0.84 | ADRB2 (0.59) | ADRB2LMNAKCNH2KDM4ETOP2A | |
| SCHEMBL2844967 | 0.83 | ADRB2 (0.68) | ADRB2KCNH2KDM4ETOP2ATOP2B | |
| SCHEMBL29492858 | 0.83 | ADRB2 (0.68) | ADRB2KCNH2KDM4ETOP2ATOP2B | |
| SCHEMBL7507103 | 0.83 | ADRB2 (0.55) | ADRB2LMNAKCNH2TOP2ATOP2B | |
| SCHEMBL7005951 | 0.82 | ADRB2 (0.57) | ADRB2LMNAKCNH2KDM4ETOP2A | |
| SCHEMBL7584091 | 0.82 | ADRB2 (0.57) | ADRB2LMNAKCNH2KDM4ETOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62059263-A | — | — | None | — | — | JP | disclosed |
| JP-S6259263-A | QUINOLONECARBOXYLIC ACID DERIVATIVE | KYORIN PHARMACEUT CO LTD | 1987-03-14 | — | — | JP | disclosed |