Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 5/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716822 | 0.89 | ADRB2 (0.55) | ADRB2KDM4EKCNH2SMN1; SMN2CYP1A2 | |
| SCHEMBL2844967 | 0.85 | ADRB2 (0.68) | ADRB2KDM4EKCNH2TOP2ATOP2B | |
| SCHEMBL29492858 | 0.85 | ADRB2 (0.68) | ADRB2KDM4EKCNH2TOP2ATOP2B | |
| SCHEMBL4713233 | 0.84 | KDM4E (0.60) | KDM4EKCNH2SMN1; SMN2CYP1A2TOP2A | |
| SCHEMBL4564641 | 0.84 | ADRB2 (0.57) | ADRB2KDM4EKCNH2TOP2ATOP2B | |
| SCHEMBL143605 | 0.83 | ADRB2 (0.64) | ADRB2KDM4EKCNH2TOP2ATOP2B | |
| SCHEMBL3134035 | 0.83 | ADRB2 (0.61) | ADRB2KDM4EKCNH2TOP2ATOP2B | |
| SCHEMBL10627001 | 0.83 | ADRB2 (0.66) | ADRB2KDM4EKCNH2TOP2ATOP2B | |
| SCHEMBL8735574 | 0.83 | ADRB2 (0.61) | ADRB2KDM4EKCNH2TOP2ATOP2B | |
| SCHEMBL7599453 | 0.82 | ADRB2 (0.65) | ADRB2KDM4EKCNH2TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929224-A | Novel medicine for treating hepatic encephalopathy | 大塚制药株式会社 | 2022-08-19 | — | — | CN | disclosed |