Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717542 | 0.89 | ALDH1A1 (0.62) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL10719868 | 0.85 | LMNA (0.61) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL7300031 | 0.81 | MAPT (0.67) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL10745338 | 0.80 | MAPT (0.62) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL10720150 | 0.80 | MAPT (0.69) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL7298319 | 0.78 | LMNA (0.56) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL7298819 | 0.78 | LMNA (0.53) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL10720005 | 0.78 | MAPT (0.64) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL7299206 | 0.78 | ALDH1A1 (0.67) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL10717947 | 0.78 | LMNA (0.52) | TSHRALDH1A1CYP1A2CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230110-A1 | Pharmacologically active pyrrole and pyrazole derivatives | FISONS plc (GB) | 1987-07-29 | — | — | EP | claimed |
| EP-0230110-A1 | Pharmacologically active pyrrole and pyrazole derivatives | FISONS plc (GB) | 1987-07-29 | — | — | EP | disclosed |