Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18407437 | 0.83 | HTR5A (0.38) | HTR5ABRD4CREBBPKDM1ARCOR1 | |
| SCHEMBL17121967 | 0.82 | MAPT (0.45) | HTR5AKMT2AALDH1A1MAPTKDM1A | |
| SCHEMBL26816408 | 0.79 | KDM4E (0.36) | KMT2AALDH1A1MAPTHTTKDM4E | |
| SCHEMBL11581457 | 0.76 | ALDH1A1 (0.42) | KMT2AALDH1A1MAPTHTTKDM4E | |
| SCHEMBL11127388 | 0.75 | HTR2C (0.39) | HTR5AALDH1A1MAPTHTTKDM4E | |
| SCHEMBL27306368 | 0.73 | GAA (0.36) | KMT2AALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL27306363 | 0.69 | KMT2A (0.36) | KMT2AALDH1A1MAPT | |
| SCHEMBL27306360 | 0.69 | MEN1 (0.35) | KMT2AALDH1A1MAPT | |
| SCHEMBL1118519 | 0.68 | CCKBR (0.42) | HTR5ABRD4CREBBPCYP11B1CYP11B2 | |
| SCHEMBL12141050 | 0.68 | CCKBR (0.42) | HTR5ABRD4CREBBPCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4692258-A | Tetrahydroquinolines as antioxidants for lubricants | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | claimed |
| EP-0072349-B1 | TETRAHYDROQUINOLINE AS AN ANTIOXIDANT FOR LUBRICANTS | CIBA-GEIGY AG (CH) | 1987-05-13 | — | — | EP | claimed |
| EP-0072349-A2 | Tetrahydroquinoline as an antioxidant for lubricants | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | claimed |
| US-9796678-B2 | Method for manufacturing optically active compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-24 | — | — | US | disclosed |
| US-9796678-B2 | Method for manufacturing optically active compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-24 | — | — | US | disclosed |
| US-20170022162-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-01-26 | — | — | US | disclosed |
| US-4692258-A | Tetrahydroquinolines as antioxidants for lubricants | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0072349-A2 | Tetrahydroquinoline as an antioxidant for lubricants | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022162-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE COMPOUND | C9, C5, PRMT7 | HTR5A 1789/4885KMT2A 663/4885ALDH1A1 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.