Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | BID | P55957 | 2/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL10717679 | 0.99 | THRA (0.52) | THRATHRBPPARAPPARGPTGS2 | |
| Phosphoric Acid SCHEMBL10716575 | 0.96 | THRA (0.45) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL27545083 | 0.94 | THRA (0.56) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL578948 | 0.94 | THRA (0.56) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL15648198 | 0.91 | THRA (0.49) | THRATHRBPPARAPPARGPTGS2 | |
| Tetraethylene Glycol SCHEMBL18919360 | 0.85 | THRB (0.48) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL1068574 | 0.83 | THRA (0.56) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL11255500 | 0.83 | THRA (0.66) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL302359 | 0.82 | THRA (0.55) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL6931501 | 0.81 | THRA (0.68) | THRATHRBPPARAPPARGPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4701375-A | TOPCOAT OF LUBRICANTS AND ANTIOXIDANT OF PHOSPHORIC ESTER; CURABLE BY RADIATION | TDK CORPORATION (JP) | 1987-10-20 | — | — | US | disclosed |
| US-4693934-A | SPECIFIC TAPE STIFFNESS | TDK CORPORATION (JP) | 1987-09-15 | — | — | US | disclosed |