Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 2/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533171 | 0.98 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| Hydrochloric Acid SCHEMBL192474 | 0.81 | KMT2A (0.48) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| Hydrochloric Acid SCHEMBL5697394 | 0.81 | ALDH1A1 (0.45) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| Hydrochloric Acid SCHEMBL11635871 | 0.80 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL758168 | 0.79 | KMT2A (0.49) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL8428916 | 0.79 | ALDH1A1 (0.43) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| Hydrochloric Acid SCHEMBL28065237 | 0.79 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| Bromide SCHEMBL9320690 | 0.78 | KMT2A (0.48) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| Hydrogen Sulfide SCHEMBL28295812 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL9936528 | 0.78 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12331246-B2 | Polyacrylamide-based symmetric branched polymer surfactant and a process for preparing the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2025-06-17 | — | — | US | claimed |
| CN-119529807-A | Salt-resistant anti-swelling slick water and application thereof | 中国石油化工股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119529175-A | Polyacrylamide aqueous dispersion, and synthetic method and application thereof | 中国石油化工股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119529176-A | Polyacrylamide aqueous dispersion, and synthetic method and application thereof | 中国石油化工股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-114478920-B | Polymer microsphere capable of constructing toughening network by sliding crosslinking points and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-113881000-B | Polymer microsphere and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-115707718-B | Method for regulating particle size of polymer microsphere | 中国石油化工股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-116120499-B | Preparation method of modified polyacrylamide | 河南亿群环保科技有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117777355-A | Amphoteric polyacrylamide microsphere, preparation method and application thereof | 中海油田服务股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117625154-A | Polymer gel deep profile control agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-03-01 | — | — | CN | claimed |
| US-20040162405-A1 | Composition and method for preparing novel cationic thickeners | SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES (SEPPIC) (FR) | 2004-08-19 | — | — | US | claimed |
| US-20030065058-A1 | Method and use of incorporating water soluble or water dispersible polymer(s) into a metalworking emulsifiable concentrate to form a stable metalworking emulsifiable concentrate and end use emulsion | PIEDRAHITA CARLOS A (US) | 2003-04-03 | — | — | US | claimed |
| US-6531561-B2 | Crosslinked N-alkylacrylamide polymers | SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2003-03-11 | — | — | US | claimed |
| EP-1212391-A1 | METALWORKING COMPOSITIONS AND THEIR PREPARATION | The Lubrizol Corporation (US) | 2002-06-12 | — | — | EP | claimed |
| US-20010023284-A1 | New polymers, the process for their preparation and the invert latexes containing them | SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2001-09-20 | — | — | US | claimed |
| WO-2001014505-A1 | METALWORKING COMPOSITIONS AND THEIR PREPARATION | THE LUBRIZOL CORPORATION (US) | 2001-03-01 | — | — | WO | claimed |
| US-4584339-A | TWO WATER SOLUBLE COPOLYMERS, ONE CONTAINING CATIONIC COMONOMERS, THE OTHER CONTAINING ANIONIC COMONOMERS | EXXON RESEARCH AND ENGINEERING CO. (US) | 1986-04-22 | — | — | US | claimed |
| US-4540496-A | Intramolecular polymer complexes - viscosifiers for high ionic strength drilling fluids | EXXON RESEARCH & ENGINEERING COMPANY (US) | 1985-09-10 | — | — | US | claimed |
| US-4536539-A | Dilatant behavior of interpolymer complexes in aqueous solution | EXXON RESEARCH AND ENGINEERING CO. (US) | 1985-08-20 | — | — | US | claimed |
| US-4305860-A | Stable, pumpable, solvent-free colloidal polyampholyte latices, their preparation and use in paper | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1981-12-15 | — | — | US | claimed |