Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 3/20 | 0.36 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.33 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.33 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.33 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.33 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.33 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.33 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.33 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.33 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1072129 | 0.79 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CYP2C9CYP2C19TGM2 | |
| SCHEMBL1533171 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CYP2C9CYP2C19TGM2 | |
| Hydrochloric Acid SCHEMBL11635871 | 0.75 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL20184318 | 0.71 | ALDH1A1 (0.38) | ALDH1A1CYP3A4CYP2C9CYP2C19TGM2 | |
| Hydrochloric Acid SCHEMBL6117928 | 0.69 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2C9CYP2C19TGM2 | |
| Hydrochloric Acid SCHEMBL192474 | 0.69 | KMT2A (0.48) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| Hydrochloric Acid SCHEMBL15843886 | 0.69 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CYP2C9CYP2C19TGM2 | |
| SCHEMBL24011779 | 0.68 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CYP2C9CYP2C19TGM2 | |
| SCHEMBL28872415 | 0.68 | TSHR (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19TGM2 | |
| SCHEMBL15222109 | 0.67 | ALDH1A1 (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105586025-A | High-temperature high-salinity oil reservoir polymer microsphere dispersed system modifying and flooding agent, and preparation method and application thereof | CHINA PETROLEUM & CHEM CORP | 2016-05-18 | — | — | CN | disclosed |