Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10750411 | 0.86 | LMNA (0.36) | ALDH1A1LMNATHRBAPEX1TSHR | |
| SCHEMBL10723230 | 0.80 | ALDH1A1 (0.35) | ALDH1A1LMNATSHRMAPK1NPSR1 | |
| SCHEMBL10750422 | 0.76 | LMNA (0.36) | ALDH1A1LMNATHRBAPEX1TSHR | |
| SCHEMBL10881804 | 0.76 | RECQL (0.39) | ALDH1A1LMNATHRBTSHRMAPK1 | |
| SCHEMBL10887264 | 0.76 | LMNA (0.37) | ALDH1A1LMNATHRBTSHRMAPK1 | |
| SCHEMBL10721429 | 0.74 | LMNA (0.42) | ALDH1A1LMNATHRBAPEX1TSHR | |
| SCHEMBL10721434 | 0.74 | LMNA (0.42) | ALDH1A1LMNATHRBAPEX1TSHR | |
| SCHEMBL10891577 | 0.71 | LMNA (0.31) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9494274 | 0.70 | LMNA (0.52) | ALDH1A1LMNATHRBTSHRMAPK1 | |
| SCHEMBL9494278 | 0.70 | LMNA (0.52) | ALDH1A1LMNATHRBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224515-A1 | SUBSTITUTED THIAZOLIDINYL ETHER | CIBA-GEIGY AG (CH) | 1987-06-10 | — | — | EP | disclosed |
| WO-1986007360-A1 | SUBSTITUTED THIAZOLIDINYL ETHER | CIBA-GEIGY AG (CH) | 1986-12-18 | — | — | WO | disclosed |