Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10881804 | 0.90 | RECQL (0.39) | LMNARECQLMAPK1TSHRMEN1 | |
| SCHEMBL10881709 | 0.82 | ALDH1A1 (0.49) | LMNARECQLMAPK1TSHRMEN1 | |
| SCHEMBL10721434 | 0.81 | LMNA (0.42) | LMNARECQLMAPK1TSHRMEN1 | |
| SCHEMBL10721429 | 0.81 | LMNA (0.42) | LMNARECQLMAPK1TSHRMEN1 | |
| SCHEMBL10723230 | 0.80 | ALDH1A1 (0.35) | LMNARECQLMAPK1TSHRMEN1 | |
| Phosphoric Acid SCHEMBL11089876 | 0.77 | ALDH1A1 (0.41) | LMNARECQLMAPK1TSHRMEN1 | |
| SCHEMBL10750411 | 0.77 | LMNA (0.36) | LMNARECQLMAPK1TSHRMEN1 | |
| SCHEMBL10721671 | 0.76 | ALDH1A1 (0.36) | LMNARECQLMAPK1TSHRMEN1 | |
| SCHEMBL10891577 | 0.76 | LMNA (0.31) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9494278 | 0.75 | LMNA (0.52) | LMNARECQLMAPK1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4489069-A | ANTITUMOR | CIBA-GEIGY AG (CH) | 1984-12-18 | — | — | US | claimed |
| US-4582841-A | ANTITUMOR AND -CARCINOGENIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| US-4489069-A | ANTITUMOR | CIBA-GEIGY AG (CH) | 1984-12-18 | — | — | US | disclosed |