Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721662 | 0.84 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2MAPTTSHR | |
| SCHEMBL27633932 | 0.74 | PDE10A (0.50) | RAB9ANPC1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL28124586 | 0.71 | HTT (0.50) | RAB9ANPC1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL226465 | 0.71 | UBE2T (0.70) | RAB9ANPC1SMN1; SMN2MAPTTSHR | |
| SCHEMBL7697161 | 0.71 | MAOA (0.43) | RAB9AMAPTHTT | |
| SCHEMBL13461926 | 0.71 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2MAPTTSHR | |
| SCHEMBL9018537 | 0.70 | UBE2T (0.54) | RAB9ANPC1SMN1; SMN2MAPTTSHR | |
| SCHEMBL752798 | 0.70 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2MAPTTSHR | |
| SCHEMBL29407035 | 0.70 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2MAPTTSHR | |
| Bromide SCHEMBL7601035 | 0.69 | UBE2T (0.68) | RAB9ANPC1SMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223368-A1 | Substituted naphthalene derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-05-27 | — | — | EP | claimed |
| EP-0223368-A1 | Substituted naphthalene derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-05-27 | — | — | EP | disclosed |