Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685758 | 0.91 | HDAC1 (0.43) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL10401841 | 0.90 | HDAC1 (0.41) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL10721880 | 0.90 | HDAC1 (0.43) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL10643935 | 0.88 | ALDH1A1 (0.39) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL10721545 | 0.87 | ALDH1A1 (0.39) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL10874170 | 0.84 | HDAC1 (0.39) | HDAC1HDAC2ALDH1A1TSHRKMT2A | |
| SCHEMBL9347501 | 0.83 | HDAC1 (0.41) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL9814590 | 0.82 | MEN1 (0.38) | ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL11179902 | 0.82 | ALDH1A1 (0.46) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL10971675 | 0.82 | HDAC1 (0.40) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |