Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685758 | 0.90 | HDAC1 (0.43) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL10721877 | 0.90 | HDAC1 (0.41) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL10721880 | 0.89 | HDAC1 (0.43) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL9347501 | 0.82 | HDAC1 (0.41) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL10543158 | 0.81 | POLB (0.40) | ALDH1A1TSHRKMT2AMEN1GAA | |
| SCHEMBL8600205 | 0.81 | POLB (0.40) | ALDH1A1TSHRKMT2AMEN1GAA | |
| SCHEMBL11179902 | 0.81 | ALDH1A1 (0.46) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL10971675 | 0.81 | HDAC1 (0.40) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL10544295 | 0.80 | L3MBTL1 (0.36) | HDAC1HDAC2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL11404443 | 0.80 | MAPT (0.38) | HDAC1HDAC2TP53ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940702-A | Cephem compounds | BEECHAM GROUP P.L.C. (GB) | 1990-07-10 | — | — | US | disclosed |
| EP-0211656-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-02-25 | — | — | EP | disclosed |
| EP-0043205-B1 | PENICILLIN DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-09-26 | — | — | EP | disclosed |
| EP-0114750-A2 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1984-08-01 | — | — | EP | disclosed |
| US-4416883-A | ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1983-11-22 | — | — | US | disclosed |
| EP-0043205-A1 | Penicillin derivatives | BEECHAM GROUP PLC (GB) | 1982-01-06 | — | — | EP | disclosed |