Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685758 | 0.84 | HDAC1 (0.43) | HDAC1HDAC2ALDH1A1MEN1KMT2A | |
| SCHEMBL10721877 | 0.82 | HDAC1 (0.41) | HDAC1HDAC2ALDH1A1MEN1KMT2A | |
| SCHEMBL10721880 | 0.81 | HDAC1 (0.43) | HDAC1HDAC2ALDH1A1MEN1KMT2A | |
| SCHEMBL10401841 | 0.81 | HDAC1 (0.41) | HDAC1HDAC2ALDH1A1MEN1KMT2A | |
| SCHEMBL9347501 | 0.81 | HDAC1 (0.41) | HDAC1HDAC2ALDH1A1MEN1KMT2A | |
| SCHEMBL11179902 | 0.76 | ALDH1A1 (0.46) | HDAC1HDAC2ALDH1A1MEN1KMT2A | |
| SCHEMBL10971671 | 0.76 | CYP2C19 (0.43) | HDAC1HDAC2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL10544295 | 0.76 | L3MBTL1 (0.36) | HDAC1HDAC2ALDH1A1MEN1KMT2A | |
| SCHEMBL10544600 | 0.74 | ALDH1A1 (0.40) | HDAC1HDAC2ALDH1A1MEN1KMT2A | |
| SCHEMBL10544136 | 0.74 | MAPT (0.38) | HDAC1HDAC2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053815-B1 | 2-OXOAZETIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1985-05-08 | — | — | EP | disclosed |