Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 14/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 14/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTAFR | P25105 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PDE1A | P54750 | 1/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130868 | 1.00 | ALDH1A1 (0.54) | ALDH1A1PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL10453317 | 0.98 | ALDH1A1 (0.56) | ALDH1A1PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL10722325 | 0.94 | ALDH1A1 (0.56) | ALDH1A1PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL21891513 | 0.93 | ALDH1A1 (0.57) | ALDH1A1PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL28436361 | 0.91 | NAAA (0.49) | ALDH1A1PDE3AMEN1KMT2ATSHR | |
| SCHEMBL3363613 | 0.91 | ALDH1A1 (0.50) | ALDH1A1PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL28230970 | 0.91 | ALDH1A1 (0.50) | ALDH1A1PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL10723835 | 0.90 | ALDH1A1 (0.59) | ALDH1A1PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL6331038 | 0.89 | ALDH1A1 (0.49) | ALDH1A1PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL21891514 | 0.87 | ALDH1A1 (0.58) | ALDH1A1PDE3BPDE3AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663641-A | LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES | RICOH COMPANY, LTD. (JP) | 1987-05-05 | — | — | US | disclosed |