SCHEMBL10723835

SCHEMBL10723835

CN(C(=O)CCC(=O)N(C)C1CCCCC1)C1CCCCC1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
FAAH O00519 1/20 0.47
PHGDH O43175 1/20 0.47
MGLL Q99685 1/20 0.47
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
NPSR1 Q6W5P4 2/20 0.46
BACE1 P56817 1/20 0.46
PKM P14618 1/20 0.45
NPBWR1 P48145 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
NPC1 O15118 2/20 0.43
ATM Q13315 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
PDE3B Q13370 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10722325 0.91 ALDH1A1 (0.56) ALDH1A1FAAHPHGDHMGLLKMT2A
SCHEMBL10453317 0.91 ALDH1A1 (0.56) ALDH1A1FAAHPHGDHMGLLKMT2A
SCHEMBL15224297 0.90 ALDH1A1 (0.51) ALDH1A1FAAHPHGDHMGLLKMT2A
SCHEMBL26211337 0.90 ALDH1A1 (0.54) ALDH1A1FAAHPHGDHMGLLKMT2A
SCHEMBL3363066 0.90 ALDH1A1 (0.54) ALDH1A1FAAHPHGDHMGLLKMT2A
SCHEMBL26211329 0.90 ALDH1A1 (0.54) ALDH1A1FAAHPHGDHMGLLKMT2A
SCHEMBL10721996 0.90 ALDH1A1 (0.54) ALDH1A1FAAHPHGDHMGLLKMT2A
SCHEMBL26211334 0.90 ALDH1A1 (0.54) ALDH1A1FAAHPHGDHMGLLKMT2A
SCHEMBL7130868 0.90 ALDH1A1 (0.54) ALDH1A1FAAHPHGDHMGLLKMT2A
SCHEMBL5143783 0.89 ALDH1A1 (0.58) ALDH1A1FAAHPHGDHMGLLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed