Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564370 | 0.88 | KDM4E (0.43) | KDM4EPOLBHSD17B10ALDH1A1HPGD | |
| SCHEMBL11005983 | 0.83 | KDM4E (0.54) | KDM4EPOLBHSD17B10USP2ALDH1A1 | |
| SCHEMBL3880159 | 0.80 | ALDH1A1 (0.52) | KDM4EHSD17B10ALDH1A1LMNAGAA | |
| SCHEMBL4867250 | 0.77 | PLA2G2A (0.46) | KDM4EPOLBHSD17B10USP2ALDH1A1 | |
| SCHEMBL31705480 | 0.74 | KDM4E (0.54) | KDM4EPOLBHSD17B10USP2ALDH1A1 | |
| SCHEMBL7412448 | 0.74 | ALDH1A1 (0.43) | KDM4EHSD17B10ALDH1A1GAAMEN1 | |
| SCHEMBL644055 | 0.74 | KDM4E (0.57) | KDM4EPOLBHSD17B10USP2ALDH1A1 | |
| SCHEMBL23294024 | 0.72 | KDM4E (0.56) | KDM4EPOLBHSD17B10USP2ALDH1A1 | |
| SCHEMBL20589795 | 0.72 | KDM4E (0.65) | KDM4EPOLBHSD17B10USP2ALDH1A1 | |
| SCHEMBL4871213 | 0.72 | KDM4E (0.56) | KDM4EPOLBHSD17B10USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673686-A | CNS MODIFIERS, ANTI-APOMORPHINE ANTIENETIC ACITIVTY/ | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLE DE L'ILE DE FRANCE (FR) | 1987-06-16 | — | — | US | disclosed |
| US-4364867-A | URINARY SYSTEM DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE FRANCE (FR) | 1982-12-21 | — | — | US | disclosed |
| US-4263316-A | ANTISPASMODIC, FOR URINARY DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE FRANCE (FR) | 1981-04-21 | — | — | US | disclosed |
| US-4029673-A | N-(1-benzyl pyrrolidinyl 2-alkyl) substituted benzamides and derivatives thereof | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1977-06-14 | — | — | US | disclosed |