Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722267 | 0.88 | KDM4E (0.49) | KDM4ENPSR1ALDH1A1JAK2JAK1 | |
| SCHEMBL3869771 | 0.81 | CA1 (0.50) | KDM4EPKMALDH1A1HPGDHSD17B10 | |
| SCHEMBL10565520 | 0.81 | KDM4E (0.46) | KDM4ENPSR1MAPK1PKMALDH1A1 | |
| SCHEMBL10563868 | 0.80 | ALDH1A1 (0.45) | KDM4EMAPK1PKMALDH1A1HPGD | |
| SCHEMBL3878089 | 0.80 | MAPK1 (0.62) | KDM4ENPSR1MAPK1ALDH1A1TSHR | |
| SCHEMBL11150060 | 0.79 | GAA (0.50) | KDM4EMAPK1PKMALDH1A1HPGD | |
| SCHEMBL7164182 | 0.75 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPTTSHRPOLB | |
| SCHEMBL19187645 | 0.74 | METAP2 (0.50) | NPSR1ALDH1A1MAPTHTR2CTSHR | |
| SCHEMBL11159013 | 0.72 | KDM4E (0.73) | KDM4ENPSR1MAPK1PKMALDH1A1 | |
| SCHEMBL10355461 | 0.72 | ACHE (0.59) | KDM4EPKMALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816471-A | NERVOUS SYSTEM DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILLE-DE FRANCE (FR) | 1989-03-28 | — | — | US | disclosed |
| US-4673686-A | CNS MODIFIERS, ANTI-APOMORPHINE ANTIENETIC ACITIVTY/ | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLE DE L'ILE DE FRANCE (FR) | 1987-06-16 | — | — | US | disclosed |
| EP-0068700-A1 | Azobicycloalkylbenzamides, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1983-01-05 | — | — | EP | disclosed |
| US-4364867-A | URINARY SYSTEM DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE FRANCE (FR) | 1982-12-21 | — | — | US | disclosed |
| US-4263316-A | ANTISPASMODIC, FOR URINARY DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE FRANCE (FR) | 1981-04-21 | — | — | US | disclosed |