Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703115 | 0.84 | KMT2A (0.51) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28264383 | 0.81 | KDM4E (0.51) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29834958 | 0.73 | KDM4E (0.51) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8861255 | 0.73 | ALDH1A1 (0.51) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6390410 | 0.73 | KDM4E (0.51) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29580418 | 0.73 | KDM4E (0.51) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2359406 | 0.73 | KDM4E (0.51) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7898823 | 0.73 | KDM4E (0.56) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29077661 | 0.73 | KDM4E (0.47) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8362810 | 0.72 | KDM4E (0.47) | TDP1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62207264-A | — | — | None | — | — | JP | disclosed |
| CN-111484459-B | Method for synthesizing chiral 3-trifluoromethyl-3, 4-dihydroquinoxalinone by palladium-catalyzed asymmetric hydrogenation | 中国科学院大连化学物理研究所 | 2021-11-02 | — | — | CN | disclosed |
| CN-111484459-A | Method for synthesizing chiral 3-trifluoromethyl-3, 4-dihydroquinoxalinone by palladium-catalyzed asymmetric hydrogenation | 中国科学院大连化学物理研究所 | 2020-08-04 | — | — | CN | disclosed |
| JP-S62207264-A | PRODUCTION OF NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE | ASAHI GLASS CO LTD | 1987-09-11 | — | — | JP | disclosed |