Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825708 | 0.81 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9825374 | 0.78 | ABCB1 (0.50) | ALDH1A1GAA | |
| SCHEMBL10718578 | 0.77 | ABCB1 (0.45) | LMNATP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10721229 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL9714096 | 0.76 | POLB (0.56) | POLB | |
| SCHEMBL10718302 | 0.75 | POLB (0.51) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL5064076 | 0.74 | ABCB1 (0.62) | HPGDSMN1; SMN2 | |
| SCHEMBL10718172 | 0.74 | HPGD (0.42) | MEN1KMT2AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL10721420 | 0.73 | LMNA (0.44) | ALDH1A1LMNAGAANPC1MAPT | |
| SCHEMBL10720027 | 0.72 | MEN1 (0.45) | MEN1KMT2AALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |