Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.53 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29612424 | 0.91 | REN (0.59) | RENPGA5CTSD | |
| SCHEMBL10867755 | 0.85 | REN (0.51) | RENPGA5CTSD | |
| SCHEMBL23598225 | 0.85 | ACE (0.57) | REN | |
| SCHEMBL7300127 | 0.85 | ACE (0.57) | REN | |
| SCHEMBL10522069 | 0.85 | ACE (0.57) | REN | |
| SCHEMBL10420805 | 0.83 | CTSS (0.54) | REN | |
| SCHEMBL9551282 | 0.83 | CTSS (0.54) | REN | |
| SCHEMBL9876266 | 0.83 | CTSS (0.54) | REN | |
| SCHEMBL9551311 | 0.83 | REN (0.64) | REN | |
| SCHEMBL27335662 | 0.83 | CTSS (0.54) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4709010-A | TREATING OR PREVENTING HYPERTENSION OR HYPERALDESTERONISM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-11-24 | — | — | US | disclosed |