Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692978 | 0.93 | REN (0.56) | RENPGA5 | |
| SCHEMBL10722951 | 0.85 | REN (0.53) | RENCTSDPGA5 | |
| SCHEMBL29612424 | 0.82 | REN (0.59) | RENCTSDPGA5 | |
| SCHEMBL10868073 | 0.80 | REN (0.44) | RENCTSDPGA5 | |
| SCHEMBL11015609 | 0.79 | REN (0.56) | RENCTSDPGA5 | |
| SCHEMBL11033295 | 0.79 | REN (0.56) | REN | |
| SCHEMBL9692628 | 0.77 | ATM (0.56) | CTSD | |
| SCHEMBL23598225 | 0.76 | ACE (0.57) | REN | |
| SCHEMBL7300127 | 0.76 | ACE (0.57) | REN | |
| SCHEMBL10522069 | 0.76 | ACE (0.57) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0179352-A2 | Peptides | MERCK PATENT GmbH (DE) | 1986-04-30 | — | — | EP | disclosed |