Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | GAA | P10253 | 5/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 3/20 | 0.68 |
| ▸ | CASP6 | P55212 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.68 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.57 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17491050 | 0.86 | GAA (0.61) | KDM4EMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL10724419 | 0.84 | P2RY12 (0.49) | KDM4EMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL9612283 | 0.84 | GAA (0.83) | KDM4EMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL9627720 | 0.82 | RAPGEF4 (0.80) | KDM4EMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL10722454 | 0.82 | KDM4E (0.61) | KDM4EMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL7814270 | 0.81 | GAA (1.00) | KDM4EMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL8169859 | 0.77 | RAPGEF4 (0.67) | KDM4EMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL14166656 | 0.76 | GAA (0.77) | KDM4EMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL10872812 | 0.75 | MAPT (0.51) | KDM4EMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL9189649 | 0.74 | RAPGEF4 (0.97) | KDM4EMAPTALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698066-A | COMPRISING A COUPLER AND DEVELOPER; DERMATOLOGICALLY NONTOXIC | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1987-10-06 | — | — | US | disclosed |