Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.75 |
| ▸ | RECQL | P46063 | 3/20 | 0.75 |
| ▸ | CASP6 | P55212 | 3/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.75 |
| ▸ | POLB | P06746 | 2/20 | 0.75 |
| ▸ | GAA | P10253 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.75 |
| ▸ | NSD2 | O96028 | 2/20 | 0.75 |
| ▸ | APEX1 | P27695 | 1/20 | 0.75 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.75 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.71 |
| ▸ | NT5E | P21589 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.62 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9189649 | 0.91 | RAPGEF4 (0.97) | RAPGEF4ALDH1A1TDP1RECQLCASP6 | |
| SCHEMBL8169859 | 0.90 | RAPGEF4 (0.67) | RAPGEF4ALDH1A1TDP1RECQLCASP6 | |
| SCHEMBL866958 | 0.89 | RAPGEF4 (1.00) | RAPGEF4ALDH1A1TDP1RECQLCASP6 | |
| SCHEMBL29516556 | 0.89 | RAPGEF4 (1.00) | RAPGEF4ALDH1A1TDP1RECQLCASP6 | |
| Ammonia Solution, Strong SCHEMBL7551968 | 0.88 | RAPGEF4 (0.97) | RAPGEF4ALDH1A1TDP1RECQLCASP6 | |
| Hydrochloric Acid SCHEMBL8652689 | 0.88 | RAPGEF4 (0.97) | RAPGEF4ALDH1A1TDP1RECQLCASP6 | |
| SCHEMBL343582 | 0.86 | GAA (1.00) | RAPGEF4ALDH1A1TDP1RECQLCASP6 | |
| SCHEMBL30040076 | 0.86 | GAA (1.00) | RAPGEF4ALDH1A1TDP1RECQLCASP6 | |
| SCHEMBL10705815 | 0.85 | RAPGEF4 (0.85) | RAPGEF4ALDH1A1TDP1RECQLCASP6 | |
| SCHEMBL9153370 | 0.85 | ALDH1A1 (0.80) | RAPGEF4ALDH1A1TDP1RECQLCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080047079-A1 | Reactive Polyazo Dyes | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2008-02-28 | — | — | US | disclosed |
| EP-0260806-B1 | COLORATION PROCESS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-08 | — | — | EP | disclosed |
| US-4881942-A | HEATING, FIXING, CONTROLLING PH TO 5.8 TO 8.0 | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-11-21 | — | — | US | disclosed |
| EP-0138303-A1 | Naphthalene sulphonic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-04-24 | — | — | EP | disclosed |
| EP-0090114-A2 | Reactive dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-10-05 | — | — | EP | disclosed |
| EP-0066714-A2 | Reactive dyestuffs | BASF Aktiengesellschaft (DE) | 1982-12-15 | — | — | EP | disclosed |
| US-4300902-A | Coloration process | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-11-17 | — | — | US | disclosed |
| US-4191687-A | Reactive dyestuffs containing the residue of 1-hydroxy-7-amino-8-(5'-amino-2',4'-disulphophenylazo)naphthalene-3,6-disulphonic acid | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-03-04 | — | — | US | disclosed |