SCHEMBL9612283

SCHEMBL9612283

Cc1ccc(Nc2ccc(N)cc2)c(S(=O)(=O)O)c1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.83
MAPT P10636 4/20 0.83
ALDH1A1 P00352 4/20 0.83
KDM4E B2RXH2 3/20 0.83
TDP1 Q9NUW8 3/20 0.83
POLB P06746 2/20 0.83
RECQL P46063 2/20 0.83
CASP6 P55212 2/20 0.83
L3MBTL1 Q9Y468 2/20 0.83
MEN1 O00255 1/20 0.83
KMT2A Q03164 1/20 0.83
ELAVL1 Q15717 1/20 0.83
RAPGEF4 Q8WZA2 1/20 0.77
NSD2 O96028 1/20 0.64
APEX1 P27695 1/20 0.64
APOBEC3A P31941 1/20 0.64
APOBEC3G Q9HC16 1/20 0.64
NT5E P21589 1/20 0.59
GNG2 P59768 3/20 0.50
GNB1 P62873 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7814270 0.91 GAA (1.00) GAAMAPTALDH1A1KDM4ETDP1
SCHEMBL14166656 0.91 GAA (0.77) GAAMAPTALDH1A1KDM4ETDP1
SCHEMBL866958 0.87 RAPGEF4 (1.00) GAAMAPTALDH1A1KDM4ETDP1
SCHEMBL29516556 0.87 RAPGEF4 (1.00) GAAMAPTALDH1A1KDM4ETDP1
SCHEMBL13220063 0.86 GAA (0.67) GAAMAPTALDH1A1KDM4ETDP1
Ammonia Solution, Strong SCHEMBL7551968 0.86 RAPGEF4 (0.97) GAAMAPTALDH1A1KDM4ETDP1
Hydrochloric Acid SCHEMBL8652689 0.86 RAPGEF4 (0.97) GAAMAPTALDH1A1KDM4ETDP1
SCHEMBL9189649 0.85 RAPGEF4 (0.97) GAAMAPTALDH1A1KDM4ETDP1
Trimethylammonium SCHEMBL7555318 0.85 RAPGEF4 (0.88) GAAMAPTALDH1A1KDM4ETDP1
SCHEMBL10723716 0.84 KDM4E (0.68) GAAMAPTALDH1A1KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2457955-B1 Trisazo dyes for paper dyeing KEMIRA OYJ (FI) 2017-08-09 EP disclosed
US-9023118-B2 Azo dyes KEMIRA OYJ (FI) 2015-05-05 US disclosed
US-9023118-B2 Azo dyes KEMIRA OYJ (FI) 2015-05-05 US disclosed
US-20130269124-A1 AZO DYES CHROMASCAPE, LLC 2013-10-17 US disclosed
US-20130269124-A1 AZO DYES CHROMASCAPE, LLC 2013-10-17 US disclosed
WO-2012072635-A1 AZO DYES KEMIRA OYJ (FI) 2012-06-07 WO disclosed
EP-2457955-A1 Trisazo dyes for paper dyeing Kemira Oyj (FI) 2012-05-30 EP disclosed