Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | CCR1 | P32246 | 6/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28644461 | 0.90 | SMN1; SMN2 (0.58) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9386877 | 0.90 | OPRD1 (0.49) | HTTP2RX7CCR1POLBALDH1A1 | |
| SCHEMBL10722405 | 0.83 | ALDH1A1 (0.54) | HTTCCR1POLBALDH1A1MAPT | |
| SCHEMBL10756639 | 0.81 | HTT (0.64) | HTTP2RX7CCR1POLBALDH1A1 | |
| SCHEMBL8185351 | 0.78 | HTT (0.65) | HTTP2RX7POLBALDH1A1MAPT | |
| SCHEMBL10617245 | 0.77 | HTT (0.62) | HTTP2RX7POLBALDH1A1MAPT | |
| SCHEMBL3364780 | 0.76 | CYP1A2 (0.50) | HTTALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL10724188 | 0.74 | HTT (0.51) | HTTCCR1POLBALDH1A1KDM4E | |
| SCHEMBL12377256 | 0.74 | HTT (0.59) | HTTP2RX7ALDH1A1MAPTTRPA1 | |
| SCHEMBL2172294 | 0.74 | CA2 (0.61) | HTTP2RX7POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665410-A | THERMOGRAPHY | RICOH COMPANY, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4613878-A | DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS | RICOH COMPANY, LTD. (JP) | 1986-09-23 | — | — | US | disclosed |