Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 7/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721835 | 0.79 | LMNA (0.36) | NPY5RTDP1 | |
| Hydrochloric Acid SCHEMBL10721852 | 0.78 | TMEM97 (0.38) | NPY5R | |
| SCHEMBL10543762 | 0.77 | NPY5R (0.59) | NPY5R | |
| SCHEMBL10724198 | 0.76 | TMEM97 (0.41) | NPY5R | |
| Hydrochloric Acid SCHEMBL10721606 | 0.75 | TMEM97 (0.40) | NPY5R | |
| SCHEMBL10656985 | 0.74 | TMEM97 (0.40) | NPY5R | |
| SCHEMBL10720127 | 0.74 | TMEM97 (0.40) | NPY5R | |
| SCHEMBL10724191 | 0.74 | TMEM97 (0.41) | NPY5R | |
| SCHEMBL10974768 | 0.73 | TMEM97 (0.47) | NPY5RMEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL10723941 | 0.73 | TMEM97 (0.39) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232740-A1 | N-containing fused heterocyclic compounds, processes for the preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-19 | — | — | EP | disclosed |