Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178534 | 0.96 | KMT2A (0.71) | LMNAMAPK1HTTMAPTALDH1A1 | |
| SCHEMBL10194869 | 0.94 | NPSR1 (0.81) | LMNAMAPK1HTTMAPTALDH1A1 | |
| SCHEMBL10720828 | 0.94 | NPSR1 (0.68) | LMNAMAPK1HTTMAPTALDH1A1 | |
| SCHEMBL13211930 | 0.93 | NPSR1 (0.79) | LMNAMAPK1HTTMAPTALDH1A1 | |
| SCHEMBL763452 | 0.90 | HTT (0.78) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL14679113 | 0.90 | NPSR1 (0.79) | LMNAMAPK1HTTMAPTALDH1A1 | |
| SCHEMBL13211890 | 0.88 | NPSR1 (0.77) | LMNAMAPK1HTTMAPTALDH1A1 | |
| SCHEMBL11983548 | 0.86 | HDAC2 (0.78) | ALDH1A1NPSR1MEN1KMT2AHDAC2 | |
| SCHEMBL7386301 | 0.86 | LMNA (0.60) | LMNAMAPK1HTTMAPTALDH1A1 | |
| SCHEMBL7392982 | 0.86 | TMEM97 (0.61) | LMNAMAPK1HTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665410-A | THERMOGRAPHY | RICOH COMPANY, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4613878-A | DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS | RICOH COMPANY, LTD. (JP) | 1986-09-23 | — | — | US | disclosed |