Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.79 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13211890 | 0.99 | NPSR1 (0.77) | NPSR1TMEM97LMNAALDH1A1MAPT | |
| SCHEMBL10194869 | 0.96 | NPSR1 (0.81) | NPSR1TMEM97LMNAALDH1A1MAPT | |
| SCHEMBL13211930 | 0.94 | NPSR1 (0.79) | NPSR1TMEM97LMNAALDH1A1MAPT | |
| SCHEMBL10720828 | 0.93 | NPSR1 (0.68) | NPSR1TMEM97LMNAALDH1A1MAPT | |
| SCHEMBL10723752 | 0.90 | LMNA (0.74) | NPSR1TMEM97LMNAALDH1A1MAPT | |
| SCHEMBL279945 | 0.90 | NPSR1 (0.97) | NPSR1ALDH1A1L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL10195008 | 0.88 | NPSR1 (0.94) | NPSR1ALDH1A1SMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL7392982 | 0.88 | TMEM97 (0.61) | NPSR1TMEM97LMNAALDH1A1MAPT | |
| SCHEMBL178534 | 0.86 | KMT2A (0.71) | NPSR1TMEM97LMNAALDH1A1MAPT | |
| SCHEMBL14006003 | 0.84 | TSHR (0.70) | NPSR1LMNAALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367668-B2 | Pyridazinone derivatives | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2013-02-05 | — | — | US | disclosed |
| US-8367668-B2 | Pyridazinone derivatives | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2013-02-05 | — | — | US | disclosed |