Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392982 | 0.87 | TMEM97 (0.61) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7387080 | 0.87 | SIGMAR1 (0.63) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7388218 | 0.86 | ALDH1A1 (0.62) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7395714 | 0.86 | NPC1 (0.60) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL10723752 | 0.86 | LMNA (0.74) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7389082 | 0.84 | SMN1; SMN2 (0.55) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL10194869 | 0.83 | NPSR1 (0.81) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7392283 | 0.83 | CCR3 (0.59) | ALDH1A1SMN1; SMN2DRD2DRD3KDM4E | |
| SCHEMBL7386884 | 0.83 | POLB (0.58) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL178534 | 0.82 | KMT2A (0.71) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0774460-A1 | BENZOIC ACID COMPOUND AND USE THEREOF AS MEDICINE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |