SCHEMBL3132789

SCHEMBL3132789

O=C1C(Cl)=CC(=Nc2ccc(O)c(Cl)c2)C=C1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
TXNRD1 Q16881 1/20 0.44
TXNRD3 Q86VQ6 1/20 0.44
TXNRD2 Q9NNW7 1/20 0.44
HSD17B10 Q99714 2/20 0.38
TSHR P16473 1/20 0.38
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
BRD4 O60885 1/20 0.35
FAAH O00519 1/20 0.35
ESR2 Q92731 2/20 0.33
AURKA O14965 1/20 0.33
AURKB Q96GD4 1/20 0.33
HSD17B3 P37058 1/20 0.31
HSD17B2 P37059 1/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8954156 0.98 PTGS1 (0.45) PTGS1PTGS2TXNRD1TXNRD3TXNRD2
SCHEMBL16309127 0.84 KMT2A (0.40) PTGS1PTGS2TXNRD1TXNRD3TXNRD2
SCHEMBL107238 0.79 TXNRD1 (0.37) TXNRD1TXNRD3TXNRD2CA2CA1
SCHEMBL11771862 0.78 TXNRD1 (0.72) PTGS1PTGS2TXNRD1TXNRD3TXNRD2
SCHEMBL505621 0.77 TXNRD1 (0.36) TXNRD1TXNRD3TXNRD2CA2CA1
Water SCHEMBL28299335 0.76 TXNRD1 (0.35) TXNRD1TXNRD3TXNRD2CA2CA1
Water SCHEMBL3454312 0.76 TXNRD1 (0.35) TXNRD1TXNRD3TXNRD2CA2CA1
SCHEMBL16310730 0.73 ALDH1A1 (0.33) TXNRD1TXNRD3TXNRD2HSD17B10TSHR
SCHEMBL11318854 0.71 PTGS1 (0.44) PTGS1PTGS2TXNRD1TXNRD3TXNRD2
SCHEMBL505620 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10619178-B2 Biosensor and production method for same ARKRAY, INC. (JP) 2020-04-14 US disclosed
EP-3290523-B1 BIOSENSOR AND PRODUCTION METHOD FOR SAME ARKRAY INC (JP) 2019-01-23 EP disclosed
EP-3290523-A1 BIOSENSOR AND PRODUCTION METHOD FOR SAME ARKRAY, Inc. (JP) 2018-03-07 EP disclosed
US-20180057851-A1 Biosensor and Production Method for Same ARKRAY, INC. (JP) 2018-03-01 US disclosed
EP-1679508-B1 BIOSENSOR AND METHOD FOR PREPARATION THEREOF ARKRAY INC (JP) 2010-07-21 EP disclosed
EP-1271143-B1 Test strip having a porous filter layer ARKRAY INC (JP) 2009-05-06 EP disclosed
US-7201871-B2 Specimen having capability of separating solid component ARKRAY INC. (JP) 2007-04-10 US disclosed
US-7189576-B2 Method for measuring substance and testing piece ARKRAY INC. (JP) 2007-03-13 US disclosed
US-20070034512-A1 Biosensor and method for producing the same ARKRAY, INC. (JP) 2007-02-15 US disclosed
US-7153696-B2 Method for measuring substance and testing piece ARKRAY INC. (JP) 2006-12-26 US disclosed
US-20030180183-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-25 US disclosed
US-20030175985-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 US disclosed
US-20030175984-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 US disclosed
US-20030166295-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-04 US disclosed
US-20030044316-A1 Specimen having capability of separating solid component ARKRAY INC. (JP) 2003-03-06 US disclosed
EP-1271143-A1 SPECIMEN HAVING CAPABILITY OF SEPARATING SOLID COMPONENT ARKRAY, Inc. (JP) 2003-01-02 EP disclosed
EP-0860695-A9 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 2001-10-17 EP disclosed
EP-0860695-A1 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 1998-08-26 EP disclosed
US-3935012-A Photosensitive sheet materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-01-27 US disclosed
US-3933594-A METHOD AND DEVICE FOR DETERMINING THE CONCENTRATION OF A SUBSTANCE IN A FLUID POLAROID CORPORATION (US) 1976-01-20 US disclosed