Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26211329 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1NPSR1BACE1 | |
| SCHEMBL26211334 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1NPSR1BACE1 | |
| SCHEMBL26211327 | 0.98 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1NPSR1BACE1 | |
| SCHEMBL26211324 | 0.96 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1NPSR1BACE1 | |
| SCHEMBL26211323 | 0.90 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1NPSR1BACE1 | |
| SCHEMBL10723835 | 0.90 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1NPSR1BACE1 | |
| SCHEMBL5143783 | 0.88 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1NPSR1BACE1 | |
| SCHEMBL10453317 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1NPSR1BACE1 | |
| SCHEMBL10722325 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1NPSR1BACE1 | |
| SCHEMBL10721996 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1NPSR1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286902-A1 | LIPID NANOPARTICLE COMPOSITION | Suzhou Abogen Biosciences Co., Ltd. (CN) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286902-A1 | LIPID NANOPARTICLE COMPOSITION | CETP, NPC1, LCAT | ALDH1A1 4587/4885KMT2A 2694/4885MEN1 2081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.