Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21078267 | 0.89 | AKR1C3 (0.50) | AKR1C3L3MBTL3POLBGAAHPGD | |
| SCHEMBL10720569 | 0.88 | AKR1C3 (0.60) | AKR1C3L3MBTL3HDAC3HDAC4HDAC1 | |
| SCHEMBL10724005 | 0.85 | HPGD (0.52) | L3MBTL3POLBGAAHPGDHDAC3 | |
| SCHEMBL19479127 | 0.83 | DRD3 (0.64) | POLBGAAHPGDKMT2AMEN1 | |
| SCHEMBL10724903 | 0.82 | HDAC3 (0.56) | L3MBTL3POLBHPGDHDAC3HDAC4 | |
| SCHEMBL28204197 | 0.80 | AKR1C3 (0.49) | AKR1C3KMT2AMEN1ALDH1A1 | |
| SCHEMBL10720264 | 0.79 | HPGD (0.59) | L3MBTL3HPGDHDAC3HDAC4HDAC1 | |
| SCHEMBL17850459 | 0.79 | KMT2A (0.60) | L3MBTL3POLBGAAHPGDKMT2A | |
| SCHEMBL15317649 | 0.79 | MEN1 (0.58) | POLBHPGDKMT2AMEN1TSHR | |
| SCHEMBL12801686 | 0.78 | AKR1C3 (0.48) | AKR1C3KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665410-A | THERMOGRAPHY | RICOH COMPANY, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4663641-A | LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES | RICOH COMPANY, LTD. (JP) | 1987-05-05 | — | — | US | disclosed |