Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | RBP4 | P02753 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724025 | 0.88 | AKR1C3 (0.58) | AKR1C3L3MBTL3L3MBTL1HDAC3HDAC4 | |
| SCHEMBL10720507 | 0.86 | L3MBTL3 (0.50) | AKR1C3L3MBTL3L3MBTL1EPHX1EPHX2 | |
| SCHEMBL10723988 | 0.84 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL10723232 | 0.82 | HDAC3 (0.55) | L3MBTL3L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL10724068 | 0.81 | L3MBTL3 (0.59) | L3MBTL3L3MBTL1MGLLACHE | |
| SCHEMBL8825319 | 0.80 | ALDH1A1 (0.55) | L3MBTL1MGLLHSD11B1 | |
| SCHEMBL8825350 | 0.79 | L3MBTL1 (0.61) | L3MBTL1MGLLHSD11B1 | |
| SCHEMBL21078267 | 0.79 | AKR1C3 (0.50) | AKR1C3L3MBTL3HDAC3HDAC4HDAC1 | |
| SCHEMBL8825167 | 0.78 | MGLL (0.60) | L3MBTL1MGLLHSD11B1 | |
| SCHEMBL10724154 | 0.78 | L3MBTL3 (0.52) | L3MBTL3L3MBTL1EPHX1EPHX2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665410-A | THERMOGRAPHY | RICOH COMPANY, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4663641-A | LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES | RICOH COMPANY, LTD. (JP) | 1987-05-05 | — | — | US | disclosed |