Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX2 | P30519 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724468 | 0.84 | POLB (0.48) | HMOX2TBXAS1ACP1CYP3A4CYP19A1 | |
| SCHEMBL10646528 | 0.83 | TBXAS1 (0.38) | HMOX2TBXAS1CYP3A4CTSAKDM4E | |
| SCHEMBL10724660 | 0.80 | MMP2 (0.36) | HMOX2TBXAS1CYP3A4CTSAKDM4E | |
| SCHEMBL10730810 | 0.80 | TBXAS1 (0.36) | HMOX2TBXAS1CYP3A4CTSAKDM4E | |
| SCHEMBL10724974 | 0.78 | TBXAS1 (0.34) | HMOX2TBXAS1CYP3A4CTSACYP19A1 | |
| SCHEMBL10729453 | 0.74 | TBXAS1 (0.46) | TBXAS1CYP3A4 | |
| SCHEMBL10729354 | 0.72 | STING1 (0.40) | TBXAS1CYP3A4 | |
| SCHEMBL10730531 | 0.71 | CYP3A4 (0.35) | TBXAS1CYP3A4KDM4E | |
| SCHEMBL10726954 | 0.71 | STING1 (0.42) | HMOX2TBXAS1CYP3A4KDM4E | |
| SCHEMBL10729834 | 0.69 | STING1 (0.44) | TBXAS1CYP3A4CYP19A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4643998-A | Imidazolylalkylthienyl tetrahydropyridazines and processes for their use | A. NATTERMAN & CIE GMBH (DE) | 1987-02-17 | — | — | US | disclosed |