Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10725215 | 0.88 | DHODH (0.51) | DHODHKDM4EALDH1A1HSD17B10KLK7 | |
| SCHEMBL16039146 | 0.85 | CYP1A1 (0.60) | KDM4EALDH1A1MAPK1TDP1MEN1 | |
| SCHEMBL7601367 | 0.83 | ABCG2 (0.54) | DHODHKDM4EALDH1A1TDP1MEN1 | |
| SCHEMBL10724373 | 0.83 | DHODH (0.59) | DHODHKDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL5781008 | 0.80 | ABCG2 (0.57) | KDM4EALDH1A1TDP1L3MBTL1MEN1 | |
| Dimethylamine SCHEMBL4104002 | 0.77 | ABCG2 (0.55) | KDM4EALDH1A1HSD17B10L3MBTL1MEN1 | |
| SCHEMBL12033647 | 0.77 | MEN1 (0.53) | DHODHKDM4EALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL28484815 | 0.77 | KDM4E (0.49) | DHODHKDM4EALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL28190057 | 0.77 | LMNA (0.53) | KDM4EALDH1A1HSD17B10L3MBTL1MEN1 | |
| SCHEMBL22542808 | 0.75 | TP53 (0.46) | DHODHKDM4EALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4639454-A | LYMPHOID LEUKEMIA | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-27 | — | — | US | disclosed |