Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751751 | 0.88 | LMNA (0.41) | SMYD3CYP1A2TSHRLMNAPOLB | |
| SCHEMBL1401913 | 0.82 | CYP1A2 (0.52) | SMYD3CYP1A2TSHRLMNAPOLB | |
| SCHEMBL10117374 | 0.79 | TSHR (0.71) | TSHRLMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL26354623 | 0.78 | TSHR (0.41) | SMYD3TSHRLMNAPOLBALDH1A1 | |
| SCHEMBL22477329 | 0.78 | MGLL (0.45) | SMYD3TSHRLMNAPOLBL3MBTL1 | |
| SCHEMBL15508181 | 0.78 | DGKA (0.52) | SMYD3TSHRPOLBALDH1A1L3MBTL1 | |
| SCHEMBL5909180 | 0.78 | LMNA (0.57) | TSHRLMNAPOLBRECQL | |
| SCHEMBL22477336 | 0.76 | MAPT (0.59) | SMYD3TSHRLMNAPOLBALDH1A1 | |
| SCHEMBL27713953 | 0.75 | DGKA (0.50) | CYP1A2TSHRLMNAALDH1A1KMT2A | |
| SCHEMBL29048644 | 0.74 | TSHR (0.41) | SMYD3CYP1A2TSHRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4696913-A | Novel peptides which are active on the central nervous system and have an action on the cholinergic system | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-29 | — | — | US | disclosed |
| US-4623715-A | ANTIDEPRESSANTS | HOECHST AKTIENGESELLESCHAFT (DE) | 1986-11-18 | — | — | US | disclosed |