Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 4/20 | 0.46 |
| ▸ | ECE1 | P42892 | 3/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | NMBR | P28336 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722606 | 1.00 | REN (0.53) | RENCTSBCTSKCASP3MME | |
| SCHEMBL10721352 | 0.93 | REN (0.52) | RENCTSBCTSKCASP3MME | |
| SCHEMBL10720793 | 0.90 | REN (0.53) | RENCTSBCTSKCASP3MME | |
| SCHEMBL10724555 | 0.90 | REN (0.53) | RENCTSBCTSKCASP3MME | |
| SCHEMBL10725310 | 0.90 | REN (0.53) | RENCTSBCTSKCASP3MME | |
| SCHEMBL10720911 | 0.88 | REN (0.51) | RENCTSBCTSKCASP3MME | |
| SCHEMBL10724617 | 0.88 | REN (0.51) | RENCTSBCTSKCASP3MME | |
| SCHEMBL10721069 | 0.86 | REN (0.54) | RENCTSBCTSKCASP3MME | |
| SCHEMBL10981168 | 0.85 | REN (0.58) | RENCTSBCTSKCASP3ERAP1 | |
| SCHEMBL10636529 | 0.85 | REN (0.58) | RENCTSBCTSKCASP3ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698329-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-06 | — | — | US | disclosed |