Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423207 | 0.74 | PTPN1 (0.47) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30883369 | 0.72 | PTPN1 (0.46) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7024785 | 0.72 | TTR (0.49) | ALDH1A1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL29446578 | 0.69 | PTPN1 (0.46) | HDAC7KDM4E | |
| SCHEMBL8599779 | 0.68 | HDAC6 (0.44) | PLK1KMT2AMEN1SMN1; SMN2NEU3 | |
| SCHEMBL26925803 | 0.68 | TPMT (0.46) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL12825820 | 0.68 | BCAT2 (0.59) | CHEK1PLK1ALDH1A1RAB9AKMT2A | |
| SCHEMBL10479912 | 0.67 | PTPN1 (0.71) | ACLYHPGDHSD17B10 | |
| SCHEMBL6262453 | 0.67 | HNF4A (0.50) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30763496 | 0.67 | PTPN1 (0.71) | ACLYHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4681950-A | PHOTOSENSITIZERS | CIBA-GEIGY CORPORATION (US) | 1987-07-21 | — | — | US | disclosed |
| US-4585876-A | PHOTOSENSITIZERS | CIBA-GEIGY CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |