SCHEMBL107274

SCHEMBL107274

CCC(C)C(=O)CCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
KEAP1 Q14145 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.51
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
FFAR1 O14842 1/20 0.50
TSHR P16473 1/20 0.49
HDAC2 Q92769 2/20 0.47
HDAC8 Q9BY41 2/20 0.47
HDAC6 Q9UBN7 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
RAB9A P51151 1/20 0.46
HDAC3 O15379 1/20 0.46
MAPK1 P28482 1/20 0.46
ADRA1A P35348 1/20 0.46
HDAC4 P56524 1/20 0.46
SLC6A3 Q01959 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC10 Q969S8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10178819 0.89 SMN1; SMN2 (0.60) ALDH1A1SMN1; SMN2KMT2ATSHRHDAC2
SCHEMBL9255541 0.85 FFAR1 (0.65) FFAR1EPHX2L3MBTL1
SCHEMBL21468925 0.85 KEAP1 (0.59) ALDH1A1KEAP1KMT2AMEN1FFAR1
SCHEMBL21306740 0.85 KEAP1 (0.59) ALDH1A1KEAP1KMT2AMEN1FFAR1
SCHEMBL10891106 0.85 TSHR (0.62) ALDH1A1KEAP1SMN1; SMN2KMT2AMEN1
SCHEMBL28913549 0.85 ALDH1A1 (0.55) ALDH1A1KEAP1SMN1; SMN2KMT2AMEN1
SCHEMBL19817614 0.85 MEN1 (0.46) ALDH1A1KEAP1SMN1; SMN2KMT2AMEN1
SCHEMBL21100446 0.84 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2FFAR1RAB9ASLC6A3
SCHEMBL104964 0.84 ESR1 (0.49) ALDH1A1KMT2AMEN1TSHRHDAC2
SCHEMBL14112339 0.83 ALDH1A1 (0.57) ALDH1A1KEAP1SMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
US-12054761-B2 Rapid pretreatment Apalta Patents OÜ (EE) 2024-08-06 US disclosed
US-11821047-B2 High pressure zone formation for pretreatment Apalta Patent OÜ (EE) 2023-11-21 US disclosed
US-20230295678-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2023-09-21 US disclosed
EP-4098750-A1 RAPID PRETREATMENT Sweetwater Energy, Inc. (US) 2022-12-07 EP disclosed
EP-3230463-B1 RAPID PRETREATMENT SWEETWATER ENERGY INC (US) 2022-05-25 EP disclosed
US-11332723-B2 Engineered microorganisms for production of commodity chemicals and cellular biomass THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-17 US disclosed
WO-2010124147-A1 COMPOSITIONS AND METHODS FOR METHANE PRODUCTION QTEROS, INC. (US) 2010-10-28 WO disclosed
WO-2010123932-A1 COMPOSITIONS AND METHODS FOR FERMENTATION OF BIOMASS QTEROS, INC. (US) 2010-10-28 WO disclosed
US-20100268000-A1 Compositions and Methods for Fermentation of Biomass QTEROS, INC. (US) 2010-10-21 US disclosed
WO-2010104896-A1 PRODUCTION OF FERMENTIVE END PRODUCTS FROM CLOSTRIDIUM SP. QTEROS, INC. (US) 2010-09-16 WO disclosed
US-20100086981-A1 COMPOSITIONS AND METHODS FOR IMPROVED SACCHARIFICATION OF BIOMASS QTEROS, INC. (US) 2010-04-08 US disclosed
US-20090203089-A1 ISOLATED ALCOHOL DEHYDROGENASE ENZYMES AND USES THEREOF BIO ARCHITECTURE LAB, INC. (US) 2009-08-13 US disclosed
WO-2009097346-A2 ISOLATED ALCOHOL DEHYDROGENASE ENZYMES AND USES THEREOF BIO ARCHITECTURE LAB, INC. (US) 2009-08-06 WO disclosed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US disclosed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA ALDH1A1 753/4885KEAP1 1425/4885SMN1; SMN2 4593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.