SCHEMBL9255541

SCHEMBL9255541

CC[C@H](C)C(=O)CCc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 10/20 0.65
FFAR4 Q5NUL3 5/20 0.65
L3MBTL1 Q9Y468 2/20 0.53
LMNA P02545 1/20 0.53
ALOX5 P09917 2/20 0.53
AKR1B1 P15121 1/20 0.52
MAOB P27338 1/20 0.51
LTA4H P09960 1/20 0.51
EPHX2 P34913 1/20 0.51
LTB4R Q15722 1/20 0.51
LTB4R2 Q9NPC1 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9261136 0.91 FFAR1 (0.57) FFAR1FFAR4L3MBTL1LMNAALOX5
SCHEMBL8010842 0.87 FFAR1 (0.70) FFAR1FFAR4AKR1B1MAOBLTA4H
SCHEMBL107274 0.85 ALDH1A1 (0.55) FFAR1L3MBTL1EPHX2
SCHEMBL14462588 0.82 L3MBTL1 (0.60) FFAR1FFAR4L3MBTL1LMNAALOX5
SCHEMBL8010686 0.80 FFAR1 (0.72) FFAR1FFAR4L3MBTL1AKR1B1MAOB
SCHEMBL5033197 0.80 FFAR1 (0.77) FFAR1FFAR4ALOX5AKR1B1MAOB
Benzyloxyphenylpropanoic Acid SCHEMBL1134648 0.79 FFAR1 (1.00) FFAR1FFAR4AKR1B1
SCHEMBL1744939 0.79 FFAR1 (1.00) FFAR1FFAR4AKR1B1
Benzyloxyphenylpropanoic Acid SCHEMBL30117578 0.78 FFAR1 (0.97) FFAR1FFAR4AKR1B1
SCHEMBL8416496 0.78 MAOB (0.59) FFAR1FFAR4L3MBTL1LMNAALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5385693-A Having rapid response and low phase transition temperature SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-31 US disclosed
EP-0357372-B1 Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL CO (JP) 1994-11-17 EP disclosed
US-5264151-A Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-23 US disclosed
US-5124070-A High speed response SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-06-23 US disclosed
EP-0357372-A2 Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-07 EP disclosed