Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732412 | 0.83 | MAPK1 (0.40) | KMT2AALDH1A1MAPTHPGDOPRM1 | |
| SCHEMBL10911480 | 0.81 | MAPT (0.38) | KMT2AALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL10735327 | 0.78 | KMT2A (0.51) | KMT2AALDH1A1MAPTHPGDHTT | |
| SCHEMBL11094467 | 0.77 | ALDH1A1 (0.38) | KMT2AALDH1A1MAPTHPGDPOLB | |
| SCHEMBL10736355 | 0.77 | POLM (0.44) | KMT2AALDH1A1OPRM1SMN1; SMN2LMNA | |
| SCHEMBL10736443 | 0.76 | KMT2A (0.49) | KMT2AALDH1A1MAPTHPGDHTT | |
| SCHEMBL10911015 | 0.74 | STK10 (0.42) | KMT2AALDH1A1MAPTHPGDHTT | |
| SCHEMBL10911473 | 0.73 | ALDH1A1 (0.34) | KMT2AALDH1A1POLBHSD17B10OPRM1 | |
| SCHEMBL11331757 | 0.73 | LMNA (0.35) | KMT2AALDH1A1MAPTPOLBHTT | |
| SCHEMBL10737255 | 0.72 | KMT2A (0.36) | KMT2AALDH1A1MAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659372-A | MITICIDE, MITE OVICIDE, AND HERBICIDES | UNION CARBIDE CORPORATION (US) | 1987-04-21 | — | — | US | disclosed |
| US-4613617-A | Synergistic insecticidal compositions containing dione esters | UNION CARBIDE CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| US-4422870-A | MITICIDE, MITE OVICIDE, HERBICIDE | UNION CARBIDE CORPORATION (US) | 1983-12-27 | — | — | US | disclosed |
| EP-0007243-B1 | 2-ARYL-1,3-CYCLOHEXANEDIONE COMPOUNDS AND ALKALI METAL SALTS, AMMONIUM SALTS AND ENOL ESTERS THEREOF, COMPOSITION AND METHOD OF CONTROLLING ACARINA ECTOPARASITES ON WARMBLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1982-11-17 | — | — | EP | disclosed |
| EP-0007243-A1 | 2-Aryl-1,3-cyclohexanedione compounds and alkali metal salts, ammonium salts and enol esters thereof, composition and method of controlling acarina ectoparasites on warmblooded animals | UNION CARBIDE CORPORATION (US) | 1980-01-23 | — | — | EP | disclosed |
| US-4175135-A | Method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animal an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound, and alkali metal salts, ammonium salts and enol esters thereof | UNION CARBIDE CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |