Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10731442 | 0.84 | KMT2A (0.41) | KMT2ASMN1; SMN2ALDH1A1HSD17B10GSK3B | |
| SCHEMBL10735327 | 0.80 | KMT2A (0.51) | KMT2ASMN1; SMN2ALDH1A1GAATDP1 | |
| SCHEMBL10911015 | 0.76 | STK10 (0.42) | KMT2ASMN1; SMN2ALDH1A1KDM4EGSK3B | |
| SCHEMBL10731396 | 0.76 | LMNA (0.41) | KMT2ASMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL10730784 | 0.74 | LMNA (0.38) | KMT2ASMN1; SMN2ALDH1A1TDP1LMNA | |
| SCHEMBL10736061 | 0.70 | GAA (0.39) | SMN1; SMN2GAALMNAL3MBTL1NPSR1 | |
| SCHEMBL10736443 | 0.70 | KMT2A (0.49) | KMT2ASMN1; SMN2ALDH1A1GAATDP1 | |
| SCHEMBL10913322 | 0.69 | KMT2A (0.35) | KMT2ASMN1; SMN2KDM4EALOX15LMNA | |
| SCHEMBL10732412 | 0.66 | MAPK1 (0.40) | KMT2ASMN1; SMN2ALDH1A1GAARECQL | |
| SCHEMBL11522683 | 0.65 | LOXL2 (0.53) | KMT2ASMN1; SMN2ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659372-A | MITICIDE, MITE OVICIDE, AND HERBICIDES | UNION CARBIDE CORPORATION (US) | 1987-04-21 | — | — | US | disclosed |
| US-4422870-A | MITICIDE, MITE OVICIDE, HERBICIDE | UNION CARBIDE CORPORATION (US) | 1983-12-27 | — | — | US | disclosed |
| US-4175135-A | Method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animal an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound, and alkali metal salts, ammonium salts and enol esters thereof | UNION CARBIDE CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |